SCHEMBL777869

SCHEMBL777869

CC(=O)OCc1ccccc1Br

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
RAB9A P51151 2/20 0.57
KMT2A Q03164 2/20 0.57
POLB P06746 1/20 0.57
PKM P14618 1/20 0.57
ALDH1A1 P00352 5/20 0.55
MMP1 P03956 1/20 0.53
MMP2 P08253 1/20 0.53
MMP9 P14780 1/20 0.53
MMP12 P39900 1/20 0.53
IDO1 P14902 2/20 0.52
NPC1 O15118 1/20 0.50
PARP10 Q53GL7 1/20 0.49
FFAR4 Q5NUL3 2/20 0.45
FFAR1 O14842 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 1/20 0.42
RIPK1 Q13546 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31554190 1.00 MAPT (0.57) MAPTRAB9AKMT2APOLBPKM
SCHEMBL28920326 0.86 ALDH1A1 (0.49) MAPTRAB9AKMT2APOLBPKM
SCHEMBL5255523 0.86 ALDH1A1 (0.65) MAPTRAB9AKMT2APOLBPKM
SCHEMBL607429 0.85 ALDH1A1 (0.47) MAPTRAB9AKMT2APOLBPKM
SCHEMBL20267396 0.84 IDO1 (0.55) MAPTRAB9AKMT2APOLBPKM
SCHEMBL7765576 0.84 MAPT (0.56) MAPTRAB9AKMT2APOLBPKM
SCHEMBL16752332 0.84 ALDH1A1 (0.46) MAPTRAB9AKMT2APOLBPKM
SCHEMBL5936403 0.82 ALDH1A1 (0.52) MAPTRAB9AKMT2APOLBPKM
SCHEMBL6702870 0.82 MMP1 (0.54) MAPTRAB9AKMT2APOLBPKM
SCHEMBL7760184 0.82 ALDH1A1 (0.56) MAPTRAB9AKMT2APOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117844320-A Corrosion-resistant heat-insulating coating for integrally assembled self-supporting steel chimney and preparation method thereof 希斯芮烟囱科技(连云港)有限公司 2024-04-09 CN claimed
CN-112010914-B Glucosamine modified pentacyclic piperazine dione and preparation and application thereof 首都医科大学 2023-06-27 CN claimed
CN-107540601-B The convenient preparation method of 5R- benzyloxy amino piperidine -2S- formic acid esters and its oxalates 新发药业有限公司 2019-07-19 CN claimed
CN-109970625-A A kind of preparation method of 5R- benzyloxy amino piperidine -2S- formic acid or derivatives thereof 新发药业有限公司 2019-07-05 CN claimed
CN-107540601-A The convenient preparation method of 5R benzyloxies amino piperidine 2S formic acid esters and its oxalates 新发药业有限公司 2018-01-05 CN claimed
CN-103920168-B Nmr sensor of tripolycyanamide and its preparation method and application is detected based on magnetic nano-particle SHANGHAI NORMAL UNIVERSITY (CN) 2016-03-30 CN claimed
CN-103920168-A Nuclear magnetic resonance sensor for detecting melamine based on magnetic nanoparticles, and preparation method and application thereof UNIV SHANGHAI 2014-07-16 CN claimed
CN-103880848-A Double-addition fulleropyrrolidine and preparation method thereof UNIV ZHENGZHOU 2014-06-25 CN claimed
CN-102295773-B Fullerene-terminated poly(benzyl aspartate) and preparation method thereof Anhui fengyuan huaihai pharmaceutical co ltd 2013-07-03 CN claimed
CN-102295773-A Fullerene-terminated poly(benzyl aspartate) and preparation method thereof 2011-12-28 CN claimed
CN-102106351-A Composition and method for inhibiting proliferation of sulfate-reducing bacteria, sheet and steel plate KOREA GAS CORP 2011-06-29 CN claimed
US-20250376443-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-12-11 US disclosed
US-20250368604-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2025-12-04 US disclosed
CN-120349255-A Synthesis method of (3-chlorophenyl ethyl) glycine benzyl ester 吉尔多肽生物制药(大连市)有限公司 2025-07-22 CN disclosed
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety CURIS INC (US) 2025-07-17 US disclosed
CN-1233237-A Heteroaryl succinamides and their use as metalloproteinase inhibitors AGOURON PHARMA (US) 1999-10-27 CN disclosed
CN-1191533-A 1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivs. as neurokinin receptor antagonists FUJISAWA PHARMACEUTICAL CO (JP) 1998-08-26 CN disclosed
CN-1090278-A Blood vessel tension peptide protoenzyme inhibitor-N-(2-amino-2-oxygen ethyl) succinic diamide derivative BIO MEGA BOEHRINGER INGELHEIM (CA) 1994-08-03 CN disclosed
CN-1087625-A N-(hydroxyethyl) succinic diamide derivative BIO MEGA BOEHRINGER INGELHEIM (CA) 1994-06-08 CN disclosed
CN-86103619-A The preparation method of the bicyclic pyrazolidinones that 7-replaces 1986-10-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety BAZ2A, BAZ2B, PI4KB MAPT 3887/4885RAB9A 2340/4885KMT2A 373/4885
US-20250368604-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, METAP2, SPINT2 MAPT 3525/4885RAB9A 2092/4885KMT2A 2987/4885
US-20250376443-A1 MASP-2 INHIBITORS AND METHODS OF USE MASP2, METAP2, SPINT2 MAPT 3707/4885RAB9A 2125/4885KMT2A 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.