Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.39 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771883 | 0.80 | TSHR (0.51) | MEN1KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL228875 | 0.72 | POLB (0.44) | FAAH | |
| SCHEMBL1128948 | 0.68 | NPC1 (0.64) | MEN1KMT2ALMNAALDH1A1REN | |
| SCHEMBL673623 | 0.67 | LMNA (0.61) | MEN1KMT2ALMNAALDH1A1REN | |
| SCHEMBL9547536 | 0.67 | LMNA (0.73) | MEN1KMT2ALMNAALDH1A1REN | |
| SCHEMBL9644840 | 0.67 | KMT2A (0.49) | MEN1KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL17732626 | 0.66 | REN (0.71) | LMNAALDH1A1RENCTSDNPSR1 | |
| SCHEMBL5146531 | 0.66 | LMNA (0.55) | MEN1KMT2ALMNAALDH1A1REN | |
| SCHEMBL29993293 | 0.66 | LMNA (0.55) | MEN1KMT2ALMNAALDH1A1REN | |
| SCHEMBL5146521 | 0.66 | LMNA (0.55) | MEN1KMT2ALMNAALDH1A1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129084-A2 | PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027832-A2 | THIAZOLE DERIVATIVES AS PPAR GAMMA LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |