Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | REN | P00797 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128947 | 0.91 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL2107224 | 0.88 | ALDH1A1 (0.53) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL28824749 | 0.86 | KMT2A (0.57) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL17732626 | 0.84 | REN (0.71) | NPC1RAB9AALDH1A1NPSR1REN | |
| SCHEMBL5146531 | 0.84 | LMNA (0.55) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL5146521 | 0.84 | LMNA (0.55) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL29993293 | 0.84 | LMNA (0.55) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL825414 | 0.83 | LMNA (0.63) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL1898753 | 0.83 | MEN1 (0.56) | NPC1RAB9AALDH1A1NPSR1MEN1 | |
| SCHEMBL7129964 | 0.83 | ALOX5 (0.66) | NPC1RAB9AALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996602-B1 | NOVEL LACTOSAMINE DERIVATIVES | GLYCOM APS (DK) | 2011-02-16 | — | — | EP | disclosed |