Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814764 | 0.86 | POLB (0.51) | POLBGBA1SLC22A1PRCPFAAH | |
| SCHEMBL28084270 | 0.81 | KDM1A (0.41) | — | |
| Hydrochloric Acid SCHEMBL29147896 | 0.80 | KDM1A (0.40) | — | |
| SCHEMBL9516562 | 0.75 | POLB (0.37) | POLBFAAH | |
| SCHEMBL28201013 | 0.73 | HSD17B3 (0.42) | POLBGBA1FAAH | |
| SCHEMBL9709040 | 0.72 | RAB9A (0.52) | POLB | |
| SCHEMBL323195 | 0.72 | KCNA3 (0.44) | HDAC8 | |
| SCHEMBL694287 | 0.70 | MAOB (0.48) | POLBGBA1 | |
| SCHEMBL9432511 | 0.70 | POLB (0.54) | POLBGBA1SLC22A1PRCP | |
| SCHEMBL450052 | 0.69 | GBA1 (0.42) | POLBGBA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 894 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003309-A | Compounds that modulate NMDA receptor activity, pharmaceutical compositions and uses thereof | 北京广为医药科技有限公司 | 2019-07-12 | — | — | CN | claimed |
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | claimed |
| US-20170112833-A1 | Tyrosine Kinase Inhibitor And Uses Thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2017-04-27 | — | — | US | claimed |
| US-9359338-B2 | Cyclopropanecarboxamido-substitute aromatic compounds as anti-tumor agents | CROWN BIOSCIENCE INC. (TAIWAN) (TW) | 2016-06-07 | — | — | US | claimed |
| US-20150197511-A1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTE AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | APOLLOMICS INC. | 2015-07-16 | — | — | US | claimed |
| EP-2864289-A1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTE AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | Crown Bioscience Inc. (Taiwan) (CN) | 2015-04-29 | — | — | EP | claimed |
| WO-2014000418-A1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTE AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CROWN BIOSCIENCE INC. (TAICANG) (CN) | 2014-01-03 | — | — | WO | claimed |
| EP-2604619-A2 | Mannose derivatives as antagonists of bacterial adhesion | University of Basel (CH) | 2013-06-19 | — | — | EP | claimed |
| WO-2012164074-A1 | MANNOSE PHOSPHATE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-12-06 | — | — | WO | claimed |
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-10-25 | — | — | US | claimed |
| WO-1998047893-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-10-29 | — | — | WO | claimed |
| EP-0772607-A1 | WATER-SOLUBLE METHINE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER COMPRISING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-14 | — | — | EP | claimed |
| US-5599825-A | ANTITUMOR AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1997-02-04 | — | — | US | claimed |
| EP-0735083-A1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1996-10-02 | — | — | EP | claimed |
| WO-1996003393-A1 | WATER-SOLUBLE METHINE COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER COMPRISING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-08 | — | — | WO | claimed |
| US-5414091-A | Compounds for thermographic images using cyan dyes | POLAROID CORPORATION (US) | 1995-05-09 | — | — | US | claimed |
| EP-0634448-A1 | Vulcanization accelerators | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1995-01-18 | — | — | EP | claimed |
| EP-0626077-A1 | IMAGE-RECORDING MATERIALS | POLAROID CORPORATION (US) | 1994-11-30 | — | — | EP | claimed |
| US-5340689-A | For diffusion transfer color process | POLAROID CORPORATION (US) | 1994-08-23 | — | — | US | claimed |
| WO-1994015256-A1 | IMAGE-RECORDING MATERIALS | POLAROID CORPORATION (US) | 1994-07-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112833-A1 | Tyrosine Kinase Inhibitor And Uses Thereof | EGFR, ERBB2, ABL1 | POLB 2203/4885GBA1 1994/4885SLC22A1 1909/4885 |
| US-20150197511-A1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTE AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | BRAF, ARAF, RAF1 | POLB 3137/4885GBA1 3435/4885SLC22A1 3935/4885 |
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | POLB 4317/4885GBA1 1038/4885SLC22A1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.