Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784512 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL7786237 | 0.76 | ALDH1A1 (0.38) | TSHR | |
| SCHEMBL6039837 | 0.76 | HPGD (0.36) | — | |
| SCHEMBL9950000 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL5735538 | 0.65 | TSHR (0.40) | TSHR | |
| SCHEMBL22281963 | 0.63 | HRH3 (0.47) | — | |
| SCHEMBL7242840 | 0.63 | MAPT (0.40) | — | |
| SCHEMBL12282193 | 0.63 | ALDH1A1 (0.45) | TSHR | |
| SCHEMBL390019 | 0.63 | ALDH1A1 (0.45) | TSHR | |
| SCHEMBL12283406 | 0.63 | ALDH1A1 (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823420-B1 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5866609-A | PROPHYLACTIC AND THERAPEUTIC AGENTS FOR ARTERIOSCLEROSIS. | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0823420-A2 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |