Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27431998 | 0.87 | ALDH1A1 (0.37) | DRD2DRD3DRD4MEN1CYP1A2 | |
| SCHEMBL7777402 | 0.83 | NOTUM (0.38) | DRD2DRD3DRD4MEN1CYP1A2 | |
| SCHEMBL9162578 | 0.81 | SLC6A2 (0.38) | HTR1ATSHRKMT2A | |
| SCHEMBL5784077 | 0.77 | ALDH1A1 (0.40) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL6825674 | 0.76 | CYP19A1 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9047485 | 0.75 | ALDH1A1 (0.41) | DRD2DRD3DRD4CHRM2CHRM1 | |
| SCHEMBL30715537 | 0.74 | ALDH1A1 (0.40) | DRD2DRD3DRD4TSHRCHRM2 | |
| SCHEMBL6825510 | 0.73 | ADRA2A (0.35) | DRD2DRD3DRD4MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7166477 | 0.72 | ADRA2A (0.34) | DRD2DRD3DRD4ALDH1A1CYP3A4 | |
| SCHEMBL22558013 | 0.71 | PTGS2 (0.45) | DRD2DRD3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |