Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280385 | 0.80 | MAPT (0.43) | MAPTALDH1A1LMNAPOLBRAB9A | |
| SCHEMBL7778351 | 0.77 | ALDH1A1 (0.42) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL7778362 | 0.74 | KDM4E (0.55) | MAPTALDH1A1LMNAPOLBRAB9A | |
| SCHEMBL29157584 | 0.74 | LMNA (0.33) | ALDH1A1LMNA | |
| SCHEMBL31612235 | 0.73 | PKM (0.35) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL31612239 | 0.73 | PKM (0.35) | MAPTALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL31612230 | 0.71 | NPC1 (0.52) | MAPTALDH1A1LMNAPOLBRAB9A | |
| SCHEMBL31612229 | 0.71 | NPC1 (0.52) | MAPTALDH1A1LMNAPOLBRAB9A | |
| SCHEMBL2458220 | 0.68 | PKM (0.44) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL9638790 | 0.67 | MAPT (0.49) | MAPTALDH1A1POLBRAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124471-B | Pyrazole ring explosive with high energy and low melting point characteristics and synthesis method thereof | 中国工程物理研究院化工材料研究所 | 2024-02-13 | — | — | CN | disclosed |
| CN-115124471-A | Pyrazole ring explosive with high-energy and low-melting-point characteristics and synthesis method thereof | 中国工程物理研究院化工材料研究所 | 2022-09-30 | — | — | CN | disclosed |
| EP-0786244-B1 | Oxidation hair-dye comprising 3,4,5 triaminopyrazole derivatives, and novel 3,4,5 triaminopyrazole derivatives | WELLA AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-5766576-A | NONTOXIC DYE DEVELOPER; WASHFASTNESS, COLORFASTNESS, RED COLOR INTENSITY | WELLA AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |
| EP-0786244-A1 | Oxidation hair-dye comprising 3,4,5 triaminopyrazole derivatives, and novel 3,4,5 triaminopyrazole derivatives | Wella Aktiengesellschaft (DE) | 1997-07-30 | — | — | EP | disclosed |