Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941289 | 0.91 | TSHR (0.34) | MMP2MMP3MMP9CYP2C9CYP2C19 | |
| SCHEMBL5872354 | 0.78 | GAA (0.35) | MMP2MMP3MMP9CYP1A2MEN1 | |
| SCHEMBL5872352 | 0.78 | GAA (0.35) | MMP2MMP3MMP9CYP1A2MEN1 | |
| SCHEMBL5872468 | 0.77 | HDAC8 (0.36) | CYP2C19CYP3A4CYP1A2KMT2A | |
| SCHEMBL5872462 | 0.77 | HDAC8 (0.36) | CYP2C19CYP3A4CYP1A2KMT2A | |
| SCHEMBL5872391 | 0.73 | CRHBP (0.38) | MMP2MMP9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL30812516 | 0.73 | CRHBP (0.38) | MMP2MMP9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL5872386 | 0.73 | CRHBP (0.38) | MMP2MMP9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL5872329 | 0.71 | CYP1A2 (0.36) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT | |
| SCHEMBL5872252 | 0.71 | CYP1A2 (0.36) | CYP2C9CYP2C19ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135349-A1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | UNIVERSITY OF DURHAM (GB) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034210-A1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | UNIVERSITY OF DURHAM (GB) | 2000-06-15 | — | — | WO | disclosed |