Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780090 | 0.91 | MMP2 (0.38) | MEN1KMT2ATDP1CYP1A2MMP2 | |
| SCHEMBL5872354 | 0.80 | GAA (0.35) | TSHRMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL5872352 | 0.80 | GAA (0.35) | TSHRMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL5872462 | 0.79 | HDAC8 (0.36) | TSHRKMT2ACYP1A2POLBCYP2C19 | |
| SCHEMBL5872468 | 0.79 | HDAC8 (0.36) | TSHRKMT2ACYP1A2POLBCYP2C19 | |
| SCHEMBL5872386 | 0.75 | CRHBP (0.38) | MEN1KMT2ACYP1A2MMP2MMP9 | |
| SCHEMBL5872391 | 0.75 | CRHBP (0.38) | MEN1KMT2ACYP1A2MMP2MMP9 | |
| SCHEMBL30812516 | 0.75 | CRHBP (0.38) | MEN1KMT2ACYP1A2MMP2MMP9 | |
| SCHEMBL5872252 | 0.73 | CYP1A2 (0.36) | TSHRMEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL5872332 | 0.73 | CYP1A2 (0.36) | TSHRMEN1KMT2ATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280757-A2 | NEW GAMMA SELECTIVE RETINOIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001083438-A2 | NEW GAMMA SELECTIVE RETINOIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-08 | — | — | WO | disclosed |