Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780176 | 0.89 | NR3C2 (0.36) | KDRGPR52RXRA | |
| SCHEMBL7776065 | 0.89 | S1PR1 (0.41) | KDRMEN1KMT2AHTR2CHTR2B | |
| SCHEMBL7782554 | 0.88 | EGFR (0.45) | KDRMEN1KMT2AHTR2CHTR2B | |
| SCHEMBL7780155 | 0.83 | PYCR1 (0.38) | — | |
| SCHEMBL7776059 | 0.83 | CNR2 (0.33) | HTR2ARXRARXRBRXRGSIGMAR1 | |
| SCHEMBL7780187 | 0.78 | HTR2B (0.36) | MEN1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL7780260 | 0.78 | RXRA (0.43) | KDRMEN1KMT2AEGFRCSF1R | |
| SCHEMBL7780255 | 0.77 | KDR (0.46) | KDRKMT2AEGFRCSF1RALDH1A1 | |
| SCHEMBL7776068 | 0.75 | PYCR1 (0.38) | RXRARXRBRXRGALDH1A1SIGMAR1 | |
| SCHEMBL7780162 | 0.74 | GPR52 (0.48) | KDREGFRGPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |