Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780291 | 0.94 | CRBN (0.33) | HTR7HTR2BTMEM97SIGMAR1CRBN | |
| SCHEMBL7781028 | 0.89 | HTR7 (0.32) | HTR7HTR2BTMEM97SIGMAR1CRBN | |
| SCHEMBL7778443 | 0.86 | CHRM2 (0.30) | — | |
| SCHEMBL3596041 | 0.84 | KMT2A (0.33) | CRBN | |
| SCHEMBL1359272 | 0.81 | HTR7 (0.32) | HTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7619891 | 0.78 | THRB (0.39) | CRBN | |
| SCHEMBL6314284 | 0.77 | L3MBTL1 (0.34) | — | |
| SCHEMBL7781016 | 0.77 | DDB1 (0.36) | CRBN | |
| SCHEMBL8648027 | 0.75 | GRIN2D (0.35) | HTR7HTR2BTMEM97SIGMAR1CRBN | |
| SCHEMBL3169698 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613885-B1 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-5567671-A | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-22 | — | — | US | disclosed |
| EP-0613885-A2 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |