Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560146 | 0.86 | ALDH1A1 (0.32) | DDB1CRBNALDH1A1CYP3A4NOS3 | |
| SCHEMBL6998330 | 0.84 | CA2 (0.38) | DDB1CRBNALDH1A1HPGDHSD17B10 | |
| SCHEMBL7780291 | 0.81 | CRBN (0.33) | DDB1CRBNKMT2AHSD17B10L3MBTL1 | |
| SCHEMBL8906325 | 0.77 | THRB (0.43) | DDB1CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL8863053 | 0.76 | KMT2A (0.42) | DDB1CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL7769002 | 0.76 | KMT2A (0.42) | DDB1CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL7766420 | 0.76 | ALDH1A1 (0.35) | DDB1CRBNALDH1A1MEN1KMT2A | |
| SCHEMBL7781028 | 0.76 | HTR7 (0.32) | CRBN | |
| SCHEMBL3596041 | 0.75 | KMT2A (0.33) | CRBNKMT2A | |
| SCHEMBL8863015 | 0.74 | MEN1 (0.35) | DDB1CRBNALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613885-B1 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-5567671-A | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-22 | — | — | US | disclosed |
| EP-0613885-A2 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |