SCHEMBL778038

SCHEMBL778038

CCO[SiH](CC(CC)NC1CCCCC1)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
SHBG P04278 1/20 0.34
THRB P10828 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
S100A4 P26447 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
CASP6 P55212 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IDO1 P14902 1/20 0.33
SLC6A4 P31645 1/20 0.32
EPHX1 P07099 1/20 0.32
EPHX2 P34913 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL773611 0.85 KDM4E (0.42) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL4522389 0.79 SHBG (0.39) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL7775156 0.78 KDM4E (0.50) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL1148861 0.78 KDM4E (0.50) KDM4ESHBGTHRBALDH1A1MEN1
Ammonia Solution, Strong SCHEMBL342936 0.76 KDM4E (0.48) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL7776985 0.75 KDM4E (0.52) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL28420942 0.73 EPHX1 (0.40) SHBGALDH1A1MEN1KMT2ASLC6A4
SCHEMBL23375445 0.71 SHBG (0.41) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL9885785 0.71 SHBG (0.41) KDM4ESHBGTHRBALDH1A1MEN1
SCHEMBL14636032 0.71 SHBG (0.41) KDM4ESHBGTHRBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606576-B2 Method for producing nitrogen-containing organoxysilane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-21 US disclosed
EP-4006042-B1 METHOD FOR PRODUCING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND SHINETSU CHEMICAL CO (JP) 2024-01-31 EP disclosed
CN-114573630-A Method for producing nitrogen-containing organooxysilane compound 信越化学工业株式会社 2022-06-03 CN disclosed
US-20220169665-A1 METHOD FOR PRODUCING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-02 US disclosed
EP-4006042-A1 METHOD FOR PRODUCING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-01 EP disclosed
US-8361176-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2013-01-29 US disclosed
EP-1907517-B1 AMINE TUNGSTATES AND DIARYLAMINES IN LUBRICANT COMPOSITIONS KING INDUSTRIES INC (US) 2012-12-05 EP disclosed
US-20120066980-A1 Hydrophilic and Hydrophobic Silane Surface Modification of Abrasive Grains SAINT-GOBAIN ABRASIFS (FR) 2012-03-22 US disclosed
US-8080500-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2011-12-20 US disclosed
US-20110282024-A1 CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES EVONIK DEGUSSA GMBH (DE) 2011-11-17 US disclosed
US-8021449-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2011-09-20 US disclosed
EP-2364241-A2 HYDROPHILIC AND HYDROPHOBIC SILANE SURFACE MODIFICATION OF ABRASIVE GRAINS Saint-Gobain Abrasives, Inc. (US) 2011-09-14 EP disclosed
US-7820602-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2010-10-26 US disclosed
US-20090260297-A1 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIFS (FR) 2009-10-22 US disclosed
WO-2009129384-A2 HYDROPHILIC AND HYDROPHOBIC SILANE SURFACE MODIFICATION OF ABRASIVE GRAINS SAINT-GOBAIN ABRASIVES, INC. (US) 2009-10-22 WO disclosed
US-20090029888-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. 2009-01-29 US disclosed
US-20080194440-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS RAVICHANDRAN RAMANATHAN 2008-08-14 US disclosed
EP-1907517-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS King Industries, Inc. (US) 2008-04-09 EP disclosed
US-20070042917-A1 Amine Tungstates and Lubricant Compositions KING INDUSTRIES, INC. 2007-02-22 US disclosed
WO-2007009022-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. (US) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606576-B2 Method for producing nitrogen-containing organoxysilane compound HRH3, HRH4, H1-0 KDM4E 2680/4885SHBG 2518/4885THRB 1649/4885
US-20110282024-A1 CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES SI, FOXO1, F11 KDM4E 581/4885SHBG 2535/4885THRB 4135/4885
US-20220169665-A1 METHOD FOR PRODUCING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND HRH3, H1-0, H1-4 KDM4E 1155/4885SHBG 3456/4885THRB 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.