Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787503 | 0.94 | POLB (0.33) | POLBALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL7780305 | 0.89 | KMT2A (0.38) | POLBALDH1A1HTTMAPKAPK2MEN1 | |
| SCHEMBL7787653 | 0.89 | KMT2A (0.38) | POLBALDH1A1HTTMAPKAPK2MEN1 | |
| SCHEMBL7785270 | 0.89 | KMT2A (0.38) | POLBALDH1A1HTTMAPKAPK2MEN1 | |
| SCHEMBL7780518 | 0.88 | MAPKAPK2 (0.34) | POLBMAPKAPK2MAPK14PLK1 | |
| SCHEMBL7780084 | 0.86 | MAPKAPK2 (0.38) | POLBALDH1A1HTTMAPKAPK2MEN1 | |
| SCHEMBL7785294 | 0.85 | ALDH1A1 (0.31) | ALDH1A1MAPTHTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7795516 | 0.84 | THRA (0.37) | POLBALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL7780353 | 0.84 | POLB (0.34) | POLBALDH1A1HTTMAPKAPK2MEN1 | |
| SCHEMBL7789041 | 0.84 | KMT2A (0.36) | POLBALDH1A1MAPTHTTMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |