Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789250 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7780432 | 0.91 | ALDH1A1 (0.41) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7780640 | 0.91 | ALDH1A1 (0.41) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7785127 | 0.91 | ALDH1A1 (0.41) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7785129 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7785574 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7784989 | 0.89 | ACP3 (0.45) | ALDH1A1LMNAGAAKMT2ACYP3A4 | |
| SCHEMBL7780321 | 0.88 | KMT2A (0.48) | ALDH1A1LMNAGAAKMT2ATP53 | |
| SCHEMBL7784915 | 0.88 | TRPM8 (0.32) | ALDH1A1LMNAGAACYP3A4KRAS | |
| SCHEMBL7785470 | 0.88 | TRPM8 (0.32) | ALDH1A1LMNAGAACYP3A4KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |