SCHEMBL8669583

SCHEMBL8669583

CCCCOc1ccccc1CC(CO)NC(=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 2/20 0.49
CTSL P07711 2/20 0.46
CTSS P25774 2/20 0.46
SYK P43405 1/20 0.45
CTSK P43235 1/20 0.45
CYP3A4 P08684 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ITGB3 P05106 6/20 0.44
ITGA2B P08514 6/20 0.44
MME P08473 1/20 0.43
ACE P12821 1/20 0.43
CPA1 P15085 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8668738 0.90 CTRB1 (0.52) CTRB1CTSLCTSSSYKCTSK
SCHEMBL8666808 0.86 ITGB3 (0.46) CTRB1CTSLCTSSSYKCTSK
SCHEMBL8668133 0.85 SIRT2 (0.52) CTSLCTSSCTSKALDH1A1ITGB3
SCHEMBL3126256 0.84 ITGB3 (0.58) CTRB1CTSLCTSSCTSKL3MBTL1
SCHEMBL14385309 0.81 CTRB1 (0.51) CTRB1CTSLCTSSSYKCTSK
SCHEMBL8775071 0.80 CTRB1 (0.57) CTRB1CYP3A4ALDH1A1TSHRL3MBTL1
SCHEMBL8749524 0.80 CYP3A4 (0.55) CTRB1CTSLCTSKCYP3A4ALDH1A1
SCHEMBL29603779 0.80 CYP3A4 (0.55) CTRB1CTSLCTSKCYP3A4ALDH1A1
SCHEMBL8352939 0.80 CTSL (0.60) CTRB1CTSLCTSSSYKCTSK
SCHEMBL31479939 0.80 CTSL (0.60) CTRB1CTSLCTSSSYKCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5853699-A Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder SCHERING AKTIENGESELLSCHAFT (DE) 1998-12-29 US disclosed
EP-0794799-A2 USE OF METAL COMPLEXES AS LIVER AND GALL BLADDER RADIODIAGNOSIS AGENTS IN COMPUTER TOMOGRAPHY SCHERING AKTIENGESELLSCHAFT (DE) 1997-09-17 EP disclosed
EP-0794800-A1 USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS SCHERING AKTIENGESELLSCHAFT (DE) 1997-09-17 EP disclosed
WO-1996016678-A1 USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS SCHERING AKTIENGESELLSCHAFT (DE) 1996-06-06 WO disclosed
WO-1996016677-A2 USE OF METAL COMPLEXES AS LIVER AND GALL BLADDER RADIODIAGNOSIS AGENTS IN COMPUTER TOMOGRAPHY SCHERING AKTIENGESELLSCHAFT (DE) 1996-06-06 WO disclosed