Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7783014 | 0.99 | STK17B (0.40) | STK17BSTK17AKMOKDRNR3C2 | |
| SCHEMBL7783732 | 0.94 | KDR (0.42) | STK17BSTK17AKDRNR3C2RAF1 | |
| SCHEMBL7780172 | 0.92 | KMO (0.43) | KMOKDRRAF1MAPK3BRAF | |
| SCHEMBL7776084 | 0.91 | NR3C2 (0.45) | STK17BSTK17AKDRNR3C2TDO2 | |
| SCHEMBL7780162 | 0.83 | GPR52 (0.48) | KDRNR3C2BRAFGRM4 | |
| Hydrochloric Acid SCHEMBL7776099 | 0.82 | GPR52 (0.48) | KDRNR3C2BRAFGRM4 | |
| SCHEMBL7781150 | 0.81 | THRB (0.55) | KDRBRAFCTSC | |
| SCHEMBL7780190 | 0.80 | THRB (0.47) | KDRNR3C2BRAFKIT | |
| Hydrochloric Acid SCHEMBL7783011 | 0.79 | THRB (0.46) | KDRNR3C2BRAFKIT | |
| SCHEMBL7776059 | 0.74 | CNR2 (0.33) | NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |