SCHEMBL778121

SCHEMBL778121

O=S(=O)(O)Cc1ccc(F)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
HTR2A P28223 6/20 0.44
HTR2C P28335 5/20 0.44
PSEN1 P49768 1/20 0.41
PSEN2 P49810 1/20 0.41
APH1B Q8WW43 1/20 0.41
NCSTN Q92542 1/20 0.41
APH1A Q96BI3 1/20 0.41
PSENEN Q9NZ42 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MAOB P27338 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
KCNH2 Q12809 2/20 0.40
RIPK1 Q13546 2/20 0.40
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4518776 0.83 IDO1 (0.48) IDO1AGXTHTR2AHTR2CPSEN1
SCHEMBL8968519 0.81 KEAP1 (0.39) IDO1AGXTHTR2AHTR2CPSEN1
SCHEMBL11703167 0.81 AKR1B1 (0.51) SMN1; SMN2
SCHEMBL776934 0.81 HTR2A (0.49) IDO1AGXTHTR2AHTR2CMAOB
SCHEMBL23706649 0.81 PSEN1 (0.42) HTR2APSEN1PSEN2APH1BNCSTN
SCHEMBL23706558 0.81 P2RX7 (0.41) KDM4ESMN1; SMN2PTGS2
SCHEMBL27619224 0.81 ADRA2B (0.41)
SCHEMBL1972231 0.80 IDO1 (0.46) IDO1AGXTHTR2AHTR2CPSEN1
SCHEMBL1271804 0.80 IDO1 (0.46) IDO1AGXTHTR2AHTR2CPSEN1
SCHEMBL3229354 0.80 IDO1 (0.50) IDO1AGXTHTR2AHTR2CPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9608291-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-28 US disclosed
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
CN-102438624-B substituted fused pyrimidine compounds ADVINUS THERAPEUTICS PRIVATE LTD. (IN) 2016-03-30 CN disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20150188192-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed