SCHEMBL776934

SCHEMBL776934

O=S(=O)(O)CCc1ccc(F)cc1F

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 15/20 0.49
HTR2C P28335 14/20 0.49
KCNH2 Q12809 7/20 0.44
DAO P14920 1/20 0.44
IDO1 P14902 2/20 0.43
AGXT P21549 2/20 0.43
MAOB P27338 1/20 0.42
DRD2 P14416 4/20 0.42
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924330 0.82 CA2 (0.40) HTR2AHTR2CKCNH2DRD2CA2
SCHEMBL11121701 0.81 HTR2A (0.41) HTR2AHTR2CKCNH2DAOIDO1
SCHEMBL778121 0.81 IDO1 (0.46) HTR2AHTR2CKCNH2DAOIDO1
SCHEMBL4705595 0.81 CA2 (0.39) HTR2AHTR2CKCNH2DRD2CA2
SCHEMBL18254264 0.78 APLNR (0.42) HTR2AHTR2CKCNH2DRD2
SCHEMBL4967989 0.77 PKM (0.34) HTR2AHTR2CCA2
SCHEMBL4968002 0.77 PSEN1 (0.36) HTR2AHTR2CCA2
SCHEMBL7700904 0.77 IDO1 (0.58) HTR2AHTR2CKCNH2DAOIDO1
SCHEMBL776466 0.77 TAAR1 (0.52) DAOIDO1MAOB
SCHEMBL778769 0.75 TAAR1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed