Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583082 | 0.76 | MAOA (0.50) | KMT2APTPN1ALDH1A1ERCC5FEN1 | |
| SCHEMBL5079244 | 0.75 | SLC6A4 (0.52) | — | |
| SCHEMBL6554492 | 0.70 | LMNA (0.49) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6585284 | 0.70 | DPP4 (0.53) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4730856 | 0.69 | GRIN1 (0.44) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL6583950 | 0.68 | HSD11B1 (0.54) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17761214 | 0.68 | PARP1 (0.47) | KMT2AADAM17ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9467270 | 0.67 | ALDH1A1 (0.54) | KMT2AALDH1A1LMNA | |
| SCHEMBL624122 | 0.67 | HSD11B1 (0.46) | — | |
| SCHEMBL5009881 | 0.66 | NR4A2 (0.65) | KMT2ANPC1RAB9ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133486-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032584-A2 | NONSTEROIDAL ANTIINFLAMMATORIES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-06-08 | — | — | WO | disclosed |