Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659131 | 0.88 | PARP10 (0.43) | TAS1R3TAS1R1TAS1R2SCN3APARP10 | |
| SCHEMBL7654129 | 0.76 | SRC (0.58) | PARP10PARP15SRC | |
| SCHEMBL7654125 | 0.76 | SRC (0.58) | PARP10PARP15SRC | |
| SCHEMBL20533142 | 0.74 | DRD2 (0.41) | TAS1R3TAS1R1TAS1R2BDKRB1CA12 | |
| SCHEMBL20533140 | 0.74 | DRD2 (0.41) | TAS1R3TAS1R1TAS1R2BDKRB1CA12 | |
| SCHEMBL20683057 | 0.74 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2BDKRB1 | |
| SCHEMBL26073271 | 0.74 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2BDKRB1 | |
| SCHEMBL3537138 | 0.73 | CFD (0.49) | TAS1R3TAS1R1TAS1R2BDKRB1ALDH1A1 | |
| SCHEMBL3537141 | 0.73 | CFD (0.49) | TAS1R3TAS1R1TAS1R2BDKRB1ALDH1A1 | |
| SCHEMBL16809810 | 0.73 | KMT2A (0.44) | TAS1R3TAS1R1TAS1R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129068-A1 | BICYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITION CONTAINING THEM AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027802-A1 | BICYCLIC SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM & USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2000-05-18 | — | — | WO | disclosed |