SCHEMBL7907283

SCHEMBL7907283

C=CCCCC[Si](C)(C)O[SiH2]C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7781874 0.91 TSHR (0.53) TSHRALDH1A1LMNA
SCHEMBL8432714 0.80 TSHR (0.41) TSHRALDH1A1LMNA
SCHEMBL7932707 0.79 TSHR (0.42) TSHRALDH1A1LMNA
SCHEMBL9155232 0.77 TSHR (0.46) TSHRALDH1A1LMNA
SCHEMBL19702985 0.77 TSHR (0.46) TSHRALDH1A1LMNA
SCHEMBL296166 0.77 ALDH1A1 (0.44) TSHRALDH1A1LMNA
SCHEMBL23499896 0.75 TSHR (0.39) TSHRALDH1A1LMNA
SCHEMBL6064484 0.75 ALDH1A1 (0.47) TSHRALDH1A1LMNA
SCHEMBL296310 0.75 ALDH1A1 (0.47) TSHRALDH1A1LMNA
SCHEMBL6064240 0.75 ALDH1A1 (0.47) TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207769-B1 A POLYMER MATRIX AND A SILOXANE-CONTAINING ADDITIVE CONTAINING ALKOXY, HYDROXY, EPOXY GROUPS WHICH IS SUBSTANTIALLY INCOMPATIBLE WITH THE POLYMER MATRIX, AND CAPABLE OF BONDING WITH SILICON ELASTOMER BY HYDROSILYLATION CURING DOW CORNING GMBH (DE) 2001-03-27 US disclosed
EP-0969048-A1 Polymer composition Dow Corning Corporation (US) 2000-01-05 EP disclosed