Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 5/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472732 | 0.92 | MAPK1 (0.46) | KMT2ALMNATNFTP53MDM2 | |
| SCHEMBL9472679 | 0.91 | TNF (0.41) | KMT2ALMNATNFTP53MDM2 | |
| SCHEMBL7226347 | 0.85 | LMNA (0.45) | KMT2ALMNATNFTP53MDM2 | |
| SCHEMBL15516519 | 0.82 | TP53 (0.55) | KMT2ALMNATP53MDM2PTPN1 | |
| SCHEMBL7774705 | 0.81 | PTPN1 (0.45) | KMT2APTPN1MEN1ALDH1A1HPGD | |
| SCHEMBL7774709 | 0.80 | MAPK1 (0.50) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL17867736 | 0.80 | TNF (0.44) | TNFPTPN1ALDH1A1TACR2CYP3A4 | |
| SCHEMBL10960740 | 0.78 | SELP (0.42) | LMNASELP | |
| SCHEMBL7774713 | 0.78 | TP53 (0.47) | KMT2ALMNATNFTP53MDM2 | |
| SCHEMBL9472943 | 0.78 | POLB (0.53) | KMT2ALMNATNFPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131311-A1 | 2-ACYLAMINO-2-DEOXY-GLUCONO-1,5-LACTONES, METHOD FOR OBTAINING SAME, COMPOSITIONS COMPRISING THEM AND USES | UNIVERSITE PIERRE ET MARIE CURIE PARIS VI (FR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031059-A1 | 2-ACYLAMINO-2-DEOXY-GLUCONO-1,5-LACTONES, METHOD FOR OBTAINING SAME, COMPOSITIONS COMPRISING THEM AND USES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI) (FR) | 2000-06-02 | — | — | WO | disclosed |