SCHEMBL7782018

SCHEMBL7782018

C=CC(NCCN(CCC)[Si](OC)(OC)OC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32
GRM7 Q14831 1/20 0.32
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10579445 0.99 ALDH1A1 (0.36) ALDH1A1POLBMAPTMTORRAB9A
SCHEMBL7783746 0.73 MTOR (0.34) ALDH1A1POLBMAPTMTORRAB9A
SCHEMBL4445401 0.72 MTOR (0.52) ALDH1A1MAPTMTORRAB9AGRM7
Hydrochloric Acid SCHEMBL10893140 0.72 LMNA (0.33) CYP3A4
Hydrochloric Acid SCHEMBL8952425 0.72 ALDH1A1 (0.50) ALDH1A1POLBMAPTMTORRAB9A
SCHEMBL4842155 0.72 HPGD (0.45) ALDH1A1MAPTMTORRAB9AGRM7
SCHEMBL1453093 0.72 ALDH1A1 (0.38) ALDH1A1POLBMAPTMTORRAB9A
SCHEMBL5361176 0.71 ALDH1A1 (0.37) ALDH1A1POLBMAPTMTORRAB9A
Hydrochloric Acid SCHEMBL22362253 0.71 ALDH1A1 (0.40) ALDH1A1POLBMAPTMTORRAB9A
SCHEMBL3293029 0.71 NAAA (0.47) ALDH1A1POLBMAPTCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0701869-B1 Protecting substrates RAYCHEM CORP (US) 2001-10-04 EP disclosed
EP-0181233-B2 Protecting substrates RAYCHEM CORP (US) 1998-09-30 EP disclosed
EP-0495560-B1 Protecting substrates RAYCHEM CORP (US) 1996-05-15 EP disclosed
EP-0701869-A1 Protecting substrates RAYCHEM CORPORATION (US) 1996-03-20 EP disclosed
EP-0495560-A1 Protecting substrates RAYCHEM CORPORATION (US) 1992-07-22 EP disclosed
US-4997685-A Applying curable mixture of polymer, curing agent and second polymeric layer, capable or interacting; curing; protective coating for pipe RAYCHEM CORPORATION (US) 1991-03-05 US disclosed
US-4732632-A Protecting elongated substrate with multiple-layer polymer covering RAYCHEM CORPORATION (US) 1988-03-22 US disclosed