SCHEMBL778237

SCHEMBL778237

Cc1cccc(P=O)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
ATM Q13315 2/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 1/20 0.38
MAPT P10636 3/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
ACHE P22303 1/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
AKR1B10 O60218 1/20 0.36
ABCB11 O95342 1/20 0.36
DHFR P00374 1/20 0.36
MPO P05164 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14067466 0.80 CA1 (0.41) TRPA1ATMKEAP1NFE2L2TSHR
SCHEMBL8652711 0.79 TRPA1 (0.46) TRPA1ATMKEAP1NFE2L2TSHR
SCHEMBL6722508 0.79
SCHEMBL5343649 0.79 TRPA1 (0.46) TRPA1ATMKEAP1NFE2L2TSHR
SCHEMBL6722506 0.79
SCHEMBL11889604 0.77 TDP2 (0.36) KEAP1NFE2L2TSHRCYP1A2CYP2A6
SCHEMBL28982499 0.76 CYP3A4 (0.56) KEAP1TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL11313735 0.75 TRPA1 (0.42) TRPA1ATMKEAP1NFE2L2TSHR
SCHEMBL7200132 0.75 TRPA1 (0.42) TRPA1ATMKEAP1NFE2L2TSHR
SCHEMBL29175963 0.73 MYC (0.48) TSHRSMN1; SMN2ALDH1A1TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591636-A Preparation method and application of novel flame retardant 安庆飞凯新材料有限公司 2025-03-11 CN claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
US-20210020838-A1 COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR AND QUANTUM DOT LIGHT-EMITTING DIODE TCL TECHNOLOGY GROUP CORPORATION (CN) 2021-01-21 US claimed
US-20210020858-A1 COMPOSITE MATERIAL AND QUANTUM DOT LIGHT EMITTING DIODE TCL TECHNOLOGY GROUP CORPORATION (CN) 2021-01-21 US claimed
CN-110890469-A Composite material and preparation method thereof TCL集团股份有限公司 2020-03-17 CN claimed
CN-102532368-B Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2014-04-02 CN claimed
CN-102532368-A Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2012-07-04 CN claimed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 US claimed
US-4013715-A PROCESS FOR THE MANUFACTURE OF 2-HALO-ETHANE-PHOSPHONIC ACID DIHALIDES AND VINYL-PHOSPHONIC ACID DIHALIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-22 US claimed
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
CN-122010983-A Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2026-05-12 CN disclosed
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-07-24 US disclosed
CN-120157693-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-17 CN disclosed
CN-120118107-A Polycyclic aromatic compound and organic electroluminescent element 爱思开新材料捷恩智株式会社 2025-06-10 CN disclosed
US-4388252-A Process for the manufacture of vinyl phosphonic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
US-4386036-A Process for the preparation of vinylphosphonic acid HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-31 US disclosed
US-4155932-A REACTING CHLORINE AND CARBON MONOXIDE WITH A TERTIARY PHOSPHINE OXIDE UBE INDUSTRIES, INC. (JP) 1979-05-22 US disclosed
US-4044060-A PHOSGENE, THIONYL, PHOSPHORUS, ALDEHYDE, KETONE BAYER AKTIENGESELLSCHAFT (DT) 1977-08-23 US disclosed
US-4013715-A PROCESS FOR THE MANUFACTURE OF 2-HALO-ETHANE-PHOSPHONIC ACID DIHALIDES AND VINYL-PHOSPHONIC ACID DIHALIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-03-22 US disclosed
US-3962324-A Process for preparing halogenomethane-phosphonic acid dihalides HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal GSDMD, PIGS, GANC TRPA1 907/4885ATM 3339/4885KEAP1 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.