Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778323 | 0.93 | LMNA (0.42) | ALDH1A1HSD11B1PTGS2MEN1KMT2A | |
| SCHEMBL8663128 | 0.84 | KDM4E (0.35) | ALDH1A1CNR2PTGS2MEN1KMT2A | |
| SCHEMBL9015117 | 0.73 | GCGR (0.50) | ALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL8798565 | 0.73 | KDM4E (0.43) | ALDH1A1POLBPTGS2MEN1KMT2A | |
| SCHEMBL29172448 | 0.71 | GCGR (0.38) | ALDH1A1PTGS2MEN1KMT2APTGS1 | |
| SCHEMBL8666601 | 0.70 | PTGS2 (0.40) | ALDH1A1PTGS2MEN1KMT2APTGS1 | |
| SCHEMBL8415325 | 0.70 | MAPK14 (0.56) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8663058 | 0.69 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL8662865 | 0.69 | MAPT (0.35) | ALDH1A1PTGS2MEN1KMT2APTGS1 | |
| SCHEMBL8779966 | 0.69 | PTGS2 (0.35) | ALDH1A1PTGS2MEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |