Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | GCGR | P47871 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784932 | 0.93 | KDM4E (0.32) | MAPK14KDM4EGCGRALDH1A1HPGD | |
| SCHEMBL7782948 | 0.83 | NISCH (0.32) | MAPK14GCGRMAPT | |
| SCHEMBL8662865 | 0.80 | MAPT (0.35) | MAPK14KDM4EGCGRALDH1A1HPGD | |
| SCHEMBL7778209 | 0.75 | PSD (0.34) | MAPK14CYP1A2GCGRMEN1KMT2A | |
| SCHEMBL7778184 | 0.73 | PSD (0.31) | MAPK14CYP1A2GCGRMEN1KMT2A | |
| SCHEMBL8798565 | 0.70 | KDM4E (0.43) | MAPK14KDM4ECYP1A2GCGRALDH1A1 | |
| SCHEMBL9015117 | 0.70 | GCGR (0.50) | MAPK14KDM4EGCGRALDH1A1HPGD | |
| SCHEMBL7782884 | 0.69 | MAPT (0.39) | MAPK14KDM4ECYP1A2GCGRALDH1A1 | |
| SCHEMBL29172448 | 0.68 | GCGR (0.38) | MAPK14KDM4EGCGRALDH1A1HPGD | |
| SCHEMBL7778323 | 0.68 | LMNA (0.42) | KDM4ECYP1A2ALDH1A1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |