Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 11/20 | 0.40 |
| ▸ | BRAF | P15056 | 4/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782975 | 0.92 | RAF1 (0.39) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL7056169 | 0.92 | KDR (0.40) | RAF1MAPK3KDRBRAF | |
| SCHEMBL7780253 | 0.85 | RAF1 (0.41) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL7780257 | 0.82 | KDR (0.43) | RAF1KDRBRAF | |
| SCHEMBL7776101 | 0.81 | KDR (0.42) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL7781138 | 0.81 | KDR (0.42) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL7783738 | 0.80 | KDR (0.39) | KDRBRAF | |
| SCHEMBL7781098 | 0.78 | KDR (0.40) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL679527 | 0.77 | KDR (0.49) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL7781117 | 0.76 | KMO (0.43) | RAF1MAPK3KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |