Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.49 |
| ▸ | BRAF | P15056 | 3/20 | 0.47 |
| ▸ | RAF1 | P04049 | 4/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885604 | 0.93 | RAF1 (0.49) | KDRBRAFRAF1MAPK3PLA2G7 | |
| SCHEMBL8773801 | 0.93 | KDR (0.47) | KDRBRAFRAF1MAPK3PLA2G7 | |
| SCHEMBL6938479 | 0.91 | KDR (0.48) | KDRBRAFHTR2ASLC6A4KCNH2 | |
| SCHEMBL7781852 | 0.87 | KDR (0.48) | KDRBRAFRAF1MAPK3HTR2A | |
| SCHEMBL8773800 | 0.87 | KDR (0.48) | KDRBRAFRAF1MAPK3HTR2A | |
| SCHEMBL7776445 | 0.87 | RAF1 (0.46) | KDRBRAFRAF1MAPK3PLA2G7 | |
| SCHEMBL8199428 | 0.86 | KDR (0.44) | KDRBRAFRAF1MAPK3HTR2A | |
| SCHEMBL7791086 | 0.86 | KDR (0.49) | KDRBRAFRAF1MAPK3PLA2G7 | |
| SCHEMBL679617 | 0.85 | RAF1 (0.45) | KDRBRAFRAF1MAPK3PLA2G7 | |
| SCHEMBL3366738 | 0.85 | EGFR (0.46) | KDRBRAFRAF1HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204167-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2010-08-12 | — | — | US | claimed |
| EP-0883991-B1 | Methods for improving the residual control of mites and prolonging the protection of plants from mite infestations | BASF AG (DE) | 2003-01-02 | — | — | EP | claimed |
| US-5883104-A | APPLYING TO THE FOLIAGE OF PLANTS AN UNSYMMETRICAL 4,6-BIS(ARYLOXY)PYRIMIDINE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1999-03-16 | — | — | US | claimed |
| EP-0883991-A1 | Methods for improving the residual control of mites and prolonging the protection of plants from mite infestations | American Cyanamid Company (US) | 1998-12-16 | — | — | EP | claimed |
| US-5707995-A | APPLYING TO SKINS/COATS OF ANIMALS TO CONTROL TICKS, INSECTS, PARASITES | AMERICAN CYANAMID COMPANY (US) | 1998-01-13 | — | — | US | claimed |
| JP-11228311-A | — | — | None | — | — | JP | disclosed |
| US-9173394-B2 | Active agent combinations having insecticidal and acaricidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-8962672-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| EP-1982594-B1 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-8299036-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20120010076-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
| US-8044085-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2011-10-25 | — | — | US | disclosed |
| US-6087498-A | Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds | AMERICAN CYANAMID COMPANY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5977363-A | Process for the preparation of unsymmetrical 4,6-bis(aryloxy) pyrimidine compounds | AMERICAN CYANAMID COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| JP-H11228311-A | IMPROVEMENT OF RESIDUAL PREVENTION OF MITE AND METHOD FOR KEEPING PLANT PROTECTION FROM PARATISM OF THE SAME | AMERICAN CYANAMID CO | 1999-08-24 | — | — | JP | disclosed |
| EP-0902020-A1 | Improved process for the preparation of unsymmetrical 4,6-bis (aryloxy) pyrimidine compounds | American Cyanamid Company (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5883104-A | APPLYING TO THE FOLIAGE OF PLANTS AN UNSYMMETRICAL 4,6-BIS(ARYLOXY)PYRIMIDINE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0883991-A1 | Methods for improving the residual control of mites and prolonging the protection of plants from mite infestations | American Cyanamid Company (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5849910-A | Process for the preparation of unsymmetrical 4,6-bis aryloxy-pyrimidine compounds | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0794177-A1 | Process for the preparation of unsymmertical 4,6-Bis (aryloxy pyrimidine compounds | American Cyanamid Company (US) | 1997-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010076-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES | ACAA2, ACHE, AADAC | KDR 4766/4885BRAF 4084/4885RAF1 3027/4885 |
| US-20100204167-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | ACHE, ACAT2, ACAT1 | KDR 4834/4885BRAF 4663/4885RAF1 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.