Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815481 | 0.85 | GAA (0.55) | CA12CA1CA2CA9MAPT | |
| SCHEMBL7588977 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL7588694 | 0.83 | RAB9A (0.51) | CA1CA2CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL3302246 | 0.81 | CA12 (0.52) | CA12CA1CA2CA9MAPT | |
| SCHEMBL7860613 | 0.80 | MTNR1A (0.56) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL7599731 | 0.78 | CNR1 (0.42) | MAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7594776 | 0.78 | HPGD (0.46) | SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL9781763 | 0.77 | CA12 (0.66) | CA12CA1CA2CA9MAPT | |
| SCHEMBL7589803 | 0.77 | CA1 (0.47) | CA12CA1CA2CA9MAPT | |
| SCHEMBL7585551 | 0.76 | CNR1 (0.46) | MAPTALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |