SCHEMBL7783113

SCHEMBL7783113

C=CC(=O)NCCC[Si](C)(C)C=C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.56
ZDHHC2 Q9UIJ5 1/20 0.56
TSHR P16473 3/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
GAA P10253 1/20 0.41
TGM2 P21980 8/20 0.38
MAPT P10636 1/20 0.35
KMT5A Q9NQR1 1/20 0.34
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 1/20 0.31
HIF1A Q16665 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6276037 0.86 ZDHHC20 (0.58) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1147756 0.84 ZDHHC20 (0.60) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL4349259 0.83 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL6276039 0.82 ZDHHC20 (0.58) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL2144275 0.81 ZDHHC20 (0.56) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL31046973 0.81 ZDHHC20 (0.56) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL632264 0.79 ZDHHC20 (0.75) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL1561467 0.79 ZDHHC20 (0.68) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9067237 0.78 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL675801 0.78 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659817-B1 Method for the preparation of an acrylic rubber-based composition NISSIN CHEMICAL IND (JP) 2001-10-10 EP disclosed
US-5585424-A Acrylic rubber-based composition NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 1996-12-17 US disclosed
EP-0659817-A1 Acrylic rubber-based composition NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 1995-06-28 EP disclosed
US-5306558-A Double-layered rubber laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-04-26 US disclosed