SCHEMBL7783181

SCHEMBL7783181

CC(=O)OCCOC(C)Oc1ccc(C=CC=Cc2ccc(O)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.43
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA7 P43166 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
MET P08581 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
APP P05067 1/20 0.39
CA2 P00918 2/20 0.39
AKR1B10 O60218 2/20 0.39
AKR1B1 P15121 2/20 0.39
ABCG2 Q9UNQ0 3/20 0.38
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
MAOB P27338 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783184 0.88 ABCG2 (0.42) STAT3CA12CA1CA7CA9
SCHEMBL7782919 0.84 ABCG2 (0.46) STAT3CA12CA1CA7CA9
SCHEMBL6833601 0.82 APP (0.43) STAT3CA12CA1CA7CA9
SCHEMBL6550242 0.82 ABCG2 (0.50) STAT3APPABCG2MAOBMAPT
SCHEMBL7784217 0.82 TAS1R3 (0.38) MAPTMEN1KMT2AKDM4ELMNA
SCHEMBL7776339 0.81 STAT3 (0.40) STAT3CA12CA1CA7CA9
SCHEMBL3264447 0.80 APP (0.47) STAT3CA12CA1CA7CA9
SCHEMBL3839200 0.79 APP (0.46) STAT3CA12CA1CA7CA9
SCHEMBL8530486 0.78 ABCG2 (0.45) STAT3CA12CA1CA7CA9
SCHEMBL6550911 0.76 APP (0.53) STAT3CA12CA1CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827970-B1 New acid-labile group protected hydroxystyrene polymers or copolymers thereof and their application to radiation sensitive materials CLARIANT FINANCE BVI LTD (VG) 2001-09-26 EP disclosed
EP-0827970-A2 New acid-labile group protected hydroxystyrene polymers or copolymers thereof and their application to radiation sensitive materials Clariant AG (CH) 1998-03-11 EP disclosed