SCHEMBL6833601

SCHEMBL6833601

CC(OCCCl)Oc1ccc(C=CC=Cc2ccc(O)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.43
STAT3 P40763 1/20 0.41
KDM4E B2RXH2 3/20 0.39
MAPT P10636 3/20 0.39
TTR P02766 2/20 0.39
CYP1A1 P04798 2/20 0.39
ALOX5 P09917 2/20 0.39
PTGS2 P35354 2/20 0.39
CYP1B1 Q16678 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPC1 O15118 1/20 0.39
ABL1 P00519 1/20 0.39
ABCB1 P08183 1/20 0.39
GAA P10253 1/20 0.39
BCR P11274 1/20 0.39
NQO2 P16083 1/20 0.39
PTGS1 P23219 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Vinylphenol SCHEMBL7711451 0.86 CHRNB2 (0.35) KDM4EMAPTTTRCYP1A1ALOX5
SCHEMBL6550242 0.86 ABCG2 (0.50) APPSTAT3KDM4EMAPTTTR
SCHEMBL3264447 0.84 APP (0.47) APPSTAT3KDM4EMAPTTTR
SCHEMBL8527423 0.84 STAT3 (0.35) APPSTAT3MAPTTTRCYP1A1
SCHEMBL3839200 0.83 APP (0.46) APPSTAT3KDM4EMAPTTTR
SCHEMBL6839679 0.82 LTB4R (0.37) CYP1A1CA12CA1CA2CA7
SCHEMBL7783181 0.82 STAT3 (0.43) APPSTAT3KDM4EMAPTTTR
SCHEMBL7776339 0.81 STAT3 (0.40) APPSTAT3KDM4EMAPTTTR
SCHEMBL6550911 0.81 APP (0.53) APPSTAT3KDM4EMAPTTTR
SCHEMBL9412360 0.80 ABL1 (0.43) KDM4EABL1BCRCHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686121-B2 WITHOUT PURIFYING RESIST MATERIALS FORMED BY REACTION, BY REACTING AN ALKALI-SOLUBLE POLYMER HAVING PHENOLIC HYDROXYL GROUPS OR CARBOXYL GROUP WITH A VINYL ETHER AND/OR DIALKYL CARBONATE IN CATALYST, APROTIC SOLVENT, ADDING ACID GENERATOR CLARIANT FINANCE (BVI) LIMITED (VG) 2004-02-03 US disclosed
EP-0942329-B1 NOVEL PROCESS FOR PREPARING RESISTS CLARIANT FINANCE BVI LTD (VG) 2002-11-13 EP disclosed
US-20010024765-A1 Novel process for preparing resists MERCK PATENT GMBH (DE) 2001-09-27 US disclosed
US-6284427-B1 Process for preparing resists CLARIANT FINANCE (BVI) LIMITED (VG) 2001-09-04 US disclosed
EP-0942329-A1 NOVEL PROCESS FOR PREPARING RESISTS Clariant International Ltd. (CH) 1999-09-15 EP disclosed