Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783228 | 0.84 | ALDH1A1 (0.34) | KDM4ENPSR1KMT2AMEN1MAPT | |
| SCHEMBL7784334 | 0.72 | ALDH1A1 (0.37) | KDM4EPKMTDP1MAPTIDO1 | |
| SCHEMBL7512827 | 0.70 | ALDH1A1 (0.47) | KDM4ECYP2C19CYP2C9NPSR1KMT2A | |
| SCHEMBL7776411 | 0.68 | MEN1 (0.35) | KDM4EPKMNPSR1KMT2AMEN1 | |
| SCHEMBL28460053 | 0.66 | SIGMAR1 (0.41) | CYP2C19CYP2C9NPSR1KMT2AMEN1 | |
| SCHEMBL7207568 | 0.66 | ATM (0.43) | KDM4ECYP2C19CYP2C9NPSR1KMT2A | |
| SCHEMBL7783261 | 0.65 | CES1 (0.40) | KDM4EPKMELANEALDH1A1HTT | |
| SCHEMBL31628334 | 0.65 | NPSR1 (0.51) | PKMCYP2C19CYP2C9NPSR1KMT2A | |
| SCHEMBL31217598 | 0.65 | ALDH1A1 (0.37) | CYP2C19CYP2C9NPSR1KMT2AMEN1 | |
| SCHEMBL12086603 | 0.65 | ALDH1A1 (0.43) | KDM4ECYP2C19CYP2C9NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | claimed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | claimed |