Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846362 | 0.98 | MAOB (0.40) | MAOBTAAR1TP53IDO1SLC6A3 | |
| SCHEMBL7782593 | 0.90 | IDO1 (0.42) | MAOBTAAR1IDO1SLC6A3 | |
| SCHEMBL7865721 | 0.84 | TAAR1 (0.45) | MAOBTAAR1RPS6KB1 | |
| SCHEMBL7846359 | 0.83 | TP53 (0.43) | TP53SLC6A3AKR1C3AKR1C2 | |
| SCHEMBL7782591 | 0.82 | ADRB2 (0.42) | TP53IDO1SLC6A3AKR1C3AKR1C2 | |
| Ammonia Solution, Strong SCHEMBL7569458 | 0.82 | IDO1 (0.40) | IDO1SLC6A3 | |
| SCHEMBL7865718 | 0.75 | PDE2A (0.42) | AKR1C3AKR1C2RPS6KB1 | |
| SCHEMBL27220940 | 0.71 | TAAR1 (0.50) | MAOBTAAR1 | |
| SCHEMBL13877352 | 0.71 | ADRB2 (0.45) | IDO1AKR1C3AKR1C2 | |
| SCHEMBL27687280 | 0.71 | IDO1 (0.62) | MAOBTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |