Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | PRCP | P42785 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783271 | 0.83 | MAOB (0.39) | TP53SLC6A3AKR1C3AKR1C2 | |
| SCHEMBL7782591 | 0.82 | ADRB2 (0.42) | TP53SLC6A3AKR1C3AKR1C2 | |
| SCHEMBL7846362 | 0.81 | MAOB (0.40) | TP53SLC6A3PRCP | |
| Ammonia Solution, Strong SCHEMBL7569458 | 0.78 | IDO1 (0.40) | SLC6A3 | |
| SCHEMBL7865718 | 0.75 | PDE2A (0.42) | AKR1C3AKR1C2 | |
| SCHEMBL7782593 | 0.73 | IDO1 (0.42) | SLC6A3 | |
| SCHEMBL13877352 | 0.71 | ADRB2 (0.45) | LMNAAKR1C3AKR1C2 | |
| SCHEMBL6819226 | 0.71 | ADRB2 (0.45) | LMNAAKR1C3AKR1C2 | |
| SCHEMBL21153574 | 0.70 | KIF11 (0.45) | — | |
| Hydrochloric Acid SCHEMBL4229200 | 0.70 | IDO1 (0.46) | AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |