Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714311 | 0.83 | TDP1 (0.38) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7784647 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL27780320 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL5739265 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL4309273 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL7783353 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNACYP2C19MAPTMAPK1 | |
| SCHEMBL10756135 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL29975243 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL3631215 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 | |
| SCHEMBL5739943 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901501-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6153744-A | LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON A DNA CHIP | WOLFGANG PFLEIDERER (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0901501-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | Pfleiderer, Wolfgang (DE) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044345-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 1997-11-27 | — | — | WO | disclosed |