Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783831 | 0.89 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL7868305 | 0.85 | ALDH1A1 (0.57) | ALDH1A1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL7717504 | 0.81 | RAB9A (0.58) | ALDH1A1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL6815182 | 0.80 | ALDH1A1 (0.63) | ALDH1A1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL7785137 | 0.74 | MEN1 (0.44) | ALDH1A1RAB9ASMN1; SMN2TP53GAA | |
| SCHEMBL7868302 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TP53MAPTKDM4ETDP1 | |
| SCHEMBL7666015 | 0.70 | GFER (0.47) | ALDH1A1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL11775119 | 0.69 | ALDH1A1 (0.63) | ALDH1A1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL28131541 | 0.68 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL7785382 | 0.68 | KMT2A (0.63) | ALDH1A1RAB9ASMN1; SMN2TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144397-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034258-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |