Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.58 |
| ▸ | NPC1 | O15118 | 10/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22983097 | 0.81 | PKM (0.66) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7783833 | 0.81 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7783831 | 0.78 | ALDH1A1 (0.44) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7716934 | 0.76 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7715871 | 0.76 | NPSR1 (0.73) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL7716927 | 0.75 | PTPN2 (0.75) | RAB9ANPC1SMN1; SMN2TP53KDM4E | |
| SCHEMBL23011774 | 0.75 | ALDH1A1 (0.84) | RAB9ANPC1SMN1; SMN2ALDH1A1CASP3 | |
| SCHEMBL3647264 | 0.75 | ALDH1A1 (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1CASP3 | |
| SCHEMBL6815182 | 0.74 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27952574 | 0.74 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |