Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 5/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787286 | 0.87 | PNMT (0.49) | PNMTPDE2ATACR1CES2GRIN2B | |
| SCHEMBL12789029 | 0.81 | PNMT (0.38) | PNMTPDE2ARAPGEF4PGK1PGK2 | |
| SCHEMBL16412648 | 0.81 | ALDH1A1 (0.36) | TACR1 | |
| SCHEMBL7786083 | 0.81 | PNMT (0.44) | PNMTPDE2ATACR1CES2GRIN2B | |
| SCHEMBL7786113 | 0.81 | PNMT (0.44) | PNMTPDE2ATACR1CES2GRIN2B | |
| SCHEMBL12789084 | 0.80 | PNMT (0.37) | PNMTPDE2ARAPGEF4TACR1PGK1 | |
| SCHEMBL7784364 | 0.79 | PNMT (0.42) | PNMTPDE2ARAPGEF4TACR1CES2 | |
| SCHEMBL15787179 | 0.79 | PNMT (0.43) | PNMTPDE2ARAPGEF4TACR1GRIN2B | |
| SCHEMBL7783846 | 0.79 | RXRA (0.41) | PNMTTACR1GRIN2B | |
| SCHEMBL17243750 | 0.79 | PNMT (0.36) | PNMTPDE2ARAPGEF4PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |