Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787286 | 0.89 | PNMT (0.49) | PNMTPDE2ACES2GRIN2BTACR1 | |
| SCHEMBL29256555 | 0.84 | PNMT (0.41) | PNMTPDE2ARXRARXRBRXRG | |
| SCHEMBL29256557 | 0.84 | PNMT (0.41) | PNMTPDE2ARXRARXRBRXRG | |
| SCHEMBL30988810 | 0.84 | PNMT (0.41) | PNMTPDE2ARXRARXRBRXRG | |
| SCHEMBL7786043 | 0.82 | CES2 (0.42) | CES2IDO1TDO2 | |
| SCHEMBL7786113 | 0.82 | PNMT (0.44) | PNMTPDE2ACES2GRIN2BTACR1 | |
| SCHEMBL7784364 | 0.81 | PNMT (0.42) | PNMTPDE2ACES2GRIN2BTACR1 | |
| SCHEMBL7783845 | 0.81 | PNMT (0.42) | PNMTPDE2ACES2GRIN2BTACR1 | |
| SCHEMBL27474110 | 0.78 | RXRA (0.39) | RXRARXRBRXRGCES2TACR1 | |
| SCHEMBL7783846 | 0.77 | RXRA (0.41) | PNMTRXRARXRBRXRGGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |