SCHEMBL7783883

SCHEMBL7783883

CCOC(=O)C(CCC1CCCC1)(C(=O)OCC)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.41
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
BCHE P06276 1/20 0.35
MMP8 P22894 1/20 0.34
SIGMAR1 Q99720 1/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 2/20 0.33
ATM Q13315 1/20 0.33
PKM P14618 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783974 0.98 METAP2 (0.43) METAP2MEN1KMT2ABCHESIGMAR1
SCHEMBL7785266 0.80 KMT2A (0.49) METAP2MEN1KMT2AALDH1A1L3MBTL1
SCHEMBL7785264 0.78 MEN1 (0.47) METAP2MEN1KMT2AALDH1A1L3MBTL1
SCHEMBL7781964 0.78 MEN1 (0.47) METAP2MEN1KMT2AALDH1A1L3MBTL1
SCHEMBL7777127 0.77 METAP2 (0.41) METAP2MEN1KMT2ABCHEMMP8
SCHEMBL11607111 0.77 MEN1 (0.44) MEN1KMT2AMMP8ALDH1A1L3MBTL1
SCHEMBL7782648 0.76 METAP2 (0.41) METAP2MEN1KMT2ABCHEMMP8
SCHEMBL7783976 0.75 METAP2 (0.36) METAP2MEN1KMT2AALDH1A1L3MBTL1
SCHEMBL16732266 0.75 MMP8 (0.37) METAP2KMT2AMMP8ALDH1A1L3MBTL1
SCHEMBL8331270 0.74 MEN1 (0.40) METAP2MEN1KMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141044-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER Basell Technology Company B.V. (NL) 2001-10-10 EP disclosed
WO-2001036496-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-05-25 WO disclosed