Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783883 | 0.98 | METAP2 (0.41) | METAP2BCHEMEN1KMT2AALDH1A1 | |
| SCHEMBL7785264 | 0.80 | MEN1 (0.47) | METAP2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7781964 | 0.80 | MEN1 (0.47) | METAP2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7785266 | 0.78 | KMT2A (0.49) | METAP2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8331270 | 0.76 | MEN1 (0.40) | METAP2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7777127 | 0.76 | METAP2 (0.41) | METAP2BCHEMEN1KMT2A | |
| SCHEMBL11607111 | 0.76 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNATHRB | |
| SCHEMBL16732196 | 0.76 | ALDH1A1 (0.38) | METAP2MEN1KMT2AALDH1A1THRB | |
| SCHEMBL7782648 | 0.75 | METAP2 (0.41) | METAP2BCHEMEN1KMT2ACYP1A2 | |
| SCHEMBL7783976 | 0.74 | METAP2 (0.36) | METAP2MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141044-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | Basell Technology Company B.V. (NL) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001036496-A1 | SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-05-25 | — | — | WO | disclosed |