Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787553 | 0.80 | KMT2A (0.34) | KMT2A | |
| SCHEMBL7786231 | 0.76 | CHRNB2 (0.47) | KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL1834987 | 0.76 | — | — | |
| SCHEMBL752438 | 0.73 | CHRNB2 (0.40) | — | |
| SCHEMBL2301489 | 0.72 | KMT2A (0.70) | KMT2ANPSR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7765233 | 0.71 | KMT2A (0.49) | KMT2ANPSR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL4984 | 0.69 | CHRNB2 (0.40) | — | |
| SCHEMBL5661852 | 0.69 | CHRNB2 (0.44) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9053082 | 0.69 | L3MBTL1 (0.36) | ALDH1A1 | |
| SCHEMBL2915925 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866609-A | PROPHYLACTIC AND THERAPEUTIC AGENTS FOR ARTERIOSCLEROSIS. | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | claimed |
| EP-0823420-A2 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | claimed |
| EP-0823420-B1 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5866609-A | PROPHYLACTIC AND THERAPEUTIC AGENTS FOR ARTERIOSCLEROSIS. | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0823420-A2 | Substituted vinylurea derivatives and their use as ACAT inhibitors | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |