Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101461 | 0.85 | MEN1 (0.33) | MEN1KMT2ACA1CA2CA4 | |
| SCHEMBL14444797 | 0.82 | DRD2 (0.34) | MEN1POLBKMT2A | |
| SCHEMBL7792739 | 0.80 | CA1 (0.35) | MEN1KMT2ACA1CA2CA4 | |
| SCHEMBL10049965 | 0.79 | MEN1 (0.33) | MEN1POLBKMT2A | |
| SCHEMBL14444798 | 0.78 | DRD2 (0.35) | MEN1POLBKMT2A | |
| SCHEMBL13766143 | 0.77 | DRD2 (0.34) | MEN1POLBKMT2A | |
| SCHEMBL25877249 | 0.76 | CHEK1 (0.31) | — | |
| SCHEMBL7264850 | 0.76 | TP53 (0.32) | MEN1KMT2A | |
| SCHEMBL13880499 | 0.75 | MEN1 (0.33) | MEN1POLBKMT2A | |
| SCHEMBL7263814 | 0.75 | ACACA (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | disclosed |