Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21877308 | 0.92 | CA1 (0.35) | CA1CA2CA4CA6ACHE | |
| SCHEMBL5101461 | 0.88 | MEN1 (0.33) | CA1CA2CA4CA6KDM4E | |
| SCHEMBL13766165 | 0.83 | MEN1 (0.33) | ACHEKDM4EALDH1A1HPGDCYP2C9 | |
| SCHEMBL21877240 | 0.82 | MAPT (0.35) | ACHEKDM4EMAPTMAPK1LMNA | |
| SCHEMBL10102196 | 0.82 | KMT2A (0.33) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14444800 | 0.81 | MEN1 (0.34) | ACHEKDM4EALDH1A1HPGDCYP2C9 | |
| SCHEMBL13880499 | 0.81 | MEN1 (0.33) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14444797 | 0.81 | DRD2 (0.34) | ACHEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7784216 | 0.80 | MEN1 (0.31) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL10102362 | 0.79 | MAPT (0.32) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | disclosed |