Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | MMP2 | P08253 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | FDPS | P14324 | 3/20 | 0.59 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790648 | 0.79 | KMT2A (0.49) | CA1CYP1A2GAAMAPTLMNA | |
| SCHEMBL3018141 | 0.78 | ALDH1A1 (0.60) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL17198268 | 0.78 | MEN1 (0.55) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL30716729 | 0.78 | ALDH1A1 (0.60) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL3933135 | 0.77 | GAA (0.55) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL7784742 | 0.76 | FDPS (0.68) | CA12MMP2CA1FDPSFDFT1 | |
| SCHEMBL5528679 | 0.75 | GAA (0.65) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL7017028 | 0.75 | MEN1 (0.53) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL2792543 | 0.75 | GAA (0.56) | CYP1A2GAAMAPTLMNAMEN1 | |
| SCHEMBL2792546 | 0.75 | GAA (0.56) | CYP1A2GAAMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |