Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395765 | 0.81 | HTT (0.61) | AOC2MAOAMAOBMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL17375204 | 0.81 | SMN1; SMN2 (0.59) | WDR5MAPTNPSR1LMNASMN1; SMN2 | |
| SCHEMBL24518872 | 0.79 | AOC2 (0.57) | AOC2MAOAMAOBMAPTALDH1A1 | |
| SCHEMBL10968374 | 0.77 | NOTUM (0.58) | MAPTALDH1A1NOTUMNPSR1MEN1 | |
| SCHEMBL4093120 | 0.77 | WDR5 (0.50) | WDR5MAPTNPSR1MEN1KMT2A | |
| SCHEMBL7776840 | 0.77 | GRM4 (0.50) | WDR5MAPTALDH1A1MEN1LMNA | |
| SCHEMBL7776851 | 0.77 | L3MBTL1 (0.49) | WDR5MAPTALDH1A1NOTUMNPSR1 | |
| SCHEMBL14499049 | 0.76 | NOTUM (0.62) | MAPTALDH1A1NOTUMNPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL6934265 | 0.76 | WDR5 (0.49) | WDR5MAPTNPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30581270 | 0.75 | KMT2A (0.50) | WDR5ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |