SCHEMBL7784850

SCHEMBL7784850

CCCc1ccc(C2CC(C)CC(C)(C)C2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
HTT P42858 2/20 0.37
SPHK1 Q9NYA1 11/20 0.37
SPHK2 Q9NRA0 7/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1858459 0.77 HTR3A (0.37) ALDH1A1HTTMEN1CYP3A4CYP2C19
SCHEMBL23071529 0.77 IDH1 (0.39) ALDH1A1HTTMEN1CYP1A2CYP3A4
SCHEMBL335898 0.77 ESR2 (0.52) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL28343291 0.77 ALDH1A1 (0.33) ALDH1A1HTTCYP1A2CYP3A4CYP2C9
SCHEMBL7133153 0.75 MAOA (0.33) ALDH1A1HTTCYP1A2CYP3A4CYP2C9
SCHEMBL11461120 0.73 ALDH1A1 (0.33) ALDH1A1HTTCYP1A2CYP3A4CYP2C9
SCHEMBL23071549 0.72 IDH1 (0.40) ALDH1A1HTTCYP1A2CYP3A4CYP2C9
Bicarbonate SCHEMBL28346273 0.72 ESR2 (0.46) ALDH1A1HTTCYP1A2CYP3A4CYP2C9
SCHEMBL4323763 0.72 SPHK1 (0.61) SPHK1SPHK2LPLLIPG
SCHEMBL10338528 0.71 SPHK1 (0.53) ALDH1A1SPHK1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141094-A1 CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS 3M Espe AG (DE) 2001-10-10 EP disclosed
WO-2000042092-A1 CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS 3M ESPE AG (DE) 2000-07-20 WO disclosed