Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 12/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784784 | 0.90 | MT-CO2 (0.39) | CA2CA1MT-CO2TOP1CA12 | |
| SCHEMBL7794482 | 0.83 | CA2 (0.38) | CA2CA1MT-CO2TOP1CA12 | |
| SCHEMBL6035717 | 0.81 | CA2 (0.54) | CA2CA1CA12ALDH1A1AKR1C3 | |
| SCHEMBL7932216 | 0.80 | AKR1C3 (0.31) | CA2CA1CA12CA3CA6 | |
| SCHEMBL7784776 | 0.79 | CA2 (0.43) | CA2CA1CA12ALDH1A1AKR1C3 | |
| SCHEMBL6035985 | 0.79 | MAPT (0.49) | MT-CO2ALDH1A1AKR1C3 | |
| SCHEMBL7938680 | 0.79 | MT-CO2 (0.32) | MT-CO2TOP1 | |
| SCHEMBL6035369 | 0.78 | CA1 (0.52) | CA2CA1CA12CA5ACA7 | |
| SCHEMBL6036055 | 0.78 | MEN1 (0.50) | CA2CA1MT-CO2TOP1CA12 | |
| SCHEMBL7804341 | 0.78 | CA2 (0.37) | CA2CA1MT-CO2TOP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140067-A1 | ANTIVIRAL METHOD USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040237-A1 | ANTIVIRAL METHOD USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |